|
|
4-hydroxybutyrate + NAD+ <=> succinate_semialdehyde + NADH + H+
|
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.61
4-hydroxybutyrate dehydrogenase
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.B47
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR29325
KEGG:
R01644
MetaCyc:
4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN
SABIO-RK:
1781
|
|
|
|
succinate_semialdehyde + NADP+ + H2O <=> NADPH + succinate + H+
|
1.1.1.21
aldose reductase
1.2.1.16
succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.79
succinate-semialdehyde dehydrogenase (NADP+)
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR29388
KEGG:
R00714
MetaCyc:
RXN0-5293;
SUCCSEMIALDDEHYDROG-RXN
SABIO-RK:
1086
|
|
|
|
succinate_semialdehyde + NAD+ + H2O <=> NADH + succinate + H+
|
1.2.1.16
succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.21
glycolaldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.79
succinate-semialdehyde dehydrogenase (NADP+)
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
|
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR29388-a
KEGG:
R00713
MetaCyc:
RXN0-5293_WOP;
SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN
SABIO-RK:
1085
|
|
|
|
4-aminobutanoate + 2-oxoglutarate <=> succinate_semialdehyde + L-glutamate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.22
(S)-3-amino-2-methylpropionate transaminase
2.6.1.29
diamine transaminase
2.6.1.48
5-aminovalerate transaminase
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47437
KEGG:
R01648
MetaCyc:
GABATRANSAM-RXN
SABIO-RK:
1785
|
|
|
|
2-oxoglutarate + H+ <=> succinate_semialdehyde + CO2
|
4.1.1.71
2-oxoglutarate decarboxylase
4.1.1.72
branched-chain-2-oxoacid decarboxylase
|
–
–
|
M
|
|
BRENDA:
BR48315
KEGG:
R00272
MetaCyc:
RXN-7774
|
|
|
|
4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + NADH + O2 + H+ <=> 2,5-dihydroxypyridine + succinate_semialdehyde + NAD+ + H2O
|
1.14.13.163
6-hydroxy-3-succinoylpyridine 3-monooxygenase
|
–
|
MK
|
|
BRENDA:
BR49101
KEGG:
R09472
MetaCyc:
RXN-13081
|
|
|
|
succinate_semialdehyde + NADP+ + CoA <=> succinyl-CoA + NADPH + H+
|
1.2.1.75
malonyl-CoA reductase (malonate semialdehyde-forming)
1.2.1.76
succinate-semialdehyde dehydrogenase (acylating)
|
–
–
|
BMK
|
|
BRENDA:
BR49114
KEGG:
R09280
MetaCyc:
RXN-8891
|
|
|
|
4-methylaminobutanoate + H2O + O2 <=> succinate_semialdehyde + methylamine + H2O2
|
1.5.3.21
4-methylaminobutanoate oxidase (methylamine-forming)
|
–
|
MK
|
|
BRENDA:
BR50154
KEGG:
R10101
MetaCyc:
RXN-13065
|
|
|
|
4-aminobutanoate + pyruvate <=> succinate_semialdehyde + L-alanine
|
2.6.1.116
6-aminohexanoate aminotransferase
2.6.1.18
beta-alanine---pyruvate transaminase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.40
(R)-3-amino-2-methylpropionate---pyruvate transaminase
2.6.1.96
4-aminobutyrate---pyruvate transaminase
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR50304
KEGG:
R10178
MetaCyc:
RXN-6902
|
|
|
|
4-aminobutanoate + glyoxylate <=> succinate_semialdehyde + glycine
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.96
4-aminobutyrate---pyruvate transaminase
|
–
–
|
|
|
BRENDA:
BR50305
KEGG:
R10179
MetaCyc:
RXN-13328
|
|
|
|
(4S)-4-hydroxy-2-oxoheptanedioate <=> succinate_semialdehyde + pyruvate
|
4.1.2.20
2-dehydro-3-deoxyglucarate aldolase
4.1.2.52
4-hydroxy-2-oxoheptanedioate aldolase
4.1.3.39
4-hydroxy-2-oxovalerate aldolase
|
–
–
–
|
BM
|
|
BRENDA:
BR50711
KEGG:
R01645
MetaCyc:
4-HYDROXY-2-KETOPIMELATE-LYSIS-RXN
SABIO-RK:
1783
|
|
|
|
NADP+ + 4-hydroxybutyrate <=> H+ + NADPH + succinate_semialdehyde
|
1.1.1
1.1.1.19
glucuronate reductase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.26
glyoxylate reductase
1.1.1.61
4-hydroxybutyrate dehydrogenase
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.B47
1.1.1.co
|
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR51069
KEGG:
R09281
MetaCyc:
RXN-11002
SABIO-RK:
10705
|
|
|
|
2-oxoglutarate + 4-hydroxybutyrate <=> succinate_semialdehyde + (R)-2-hydroxyglutarate
|
1.1.99.24
hydroxyacid-oxoacid transhydrogenase
|
–
|
|
|
BRENDA:
BS189010
MetaCyc:
RXN-14300
SABIO-RK:
10878
|
|
|
|
2-(acetylaminomethylene)succinate + H2O + H+ <=> succinate_semialdehyde + acetate + CO2 + NH3
|
3.5.1.29
2-(acetamidomethylene)succinate hydrolase
|
–
|
M
|
|
BRENDA:
BS413145
MetaCyc:
3.5.1.29-RXN
|
|
|
|
2-(Acetamidomethylene)succinate + 2 H2O <=> acetate + succinate_semialdehyde + NH3 + CO2
|
3.5.1.29
2-(acetamidomethylene)succinate hydrolase
3.5.1.66
2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase
|
–
–
|
K
|
|
BRENDA:
BR19243
KEGG:
R01649
|
|
|
|
2,4-Dihydroxyhept-2-enedioate <=> succinate_semialdehyde + pyruvate
|
4.1.2
4.1.2.52
4-hydroxy-2-oxoheptanedioate aldolase
|
–
–
|
K
|
|
KEGG:
R01647
MetaCyc:
RXN-14146
|
|
|
|
succinate_semialdehyde + cyanide + NH3 <=> gamma-Amino-gamma-cyanobutanoate + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R01650
|
|
|
|
gamma-butyrobetaine + O2 + NADPH + H+ <=> succinate_semialdehyde + trimethylamine + NADP+ + H2O
|
1.14.13.239
carnitine monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18258
|
|
|
|
gamma-butyrobetaine + O2 + NADH + H+ <=> succinate_semialdehyde + trimethylamine + NAD+ + H2O
|
1.14.13.239
carnitine monooxygenase
|
–
|
|
|
MetaCyc:
RXN-18258_WOP
|
|
|
|
4-aminobutanoate + O2 + H2O <=> succinate_semialdehyde + NH3 + H2O2
|
1.4.3.21
primary-amine oxidase
1.5.3.21
4-methylaminobutanoate oxidase (methylamine-forming)
|
–
–
|
|
|
BRENDA:
BS420028
|
|
|
|
succinate_semialdehyde + H2O + O2 <=> succinate + H2O2
|
1.17.3.2
xanthine oxidase
|
–
|
|
|
BRENDA:
BS359352
|
|
|
|
4-aminobutanoate + 2-oxoglutarate <=> succinate_semialdehyde + D-glutamate
|
2.6.1.54
pyridoxamine-phosphate transaminase
|
–
|
|
|
BRENDA:
BS354481
|
|
|
|
D-2-aminobutyrate + 2-oxoglutarate <=> succinate_semialdehyde + D-glutamate
|
2.6.1.21
D-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353642
|
|
|
|
5-hydroxybutanoate + NAD+ <=> succinate_semialdehyde + NADH + H+
|
1.1.1.61
4-hydroxybutyrate dehydrogenase
|
–
|
|
|
BRENDA:
BS451091
|
|
|
|
4-aminobutanoate + Butyraldehyde <=> succinate_semialdehyde + n-butylamine
|
2.6.1.18
beta-alanine---pyruvate transaminase
|
–
|
|
|
BRENDA:
BS436898
|
|
|
|
L-3-hydroxybutyrate + succinate_semialdehyde <=> acetoacetate + 4-hydroxybutyrate
|
1.1.99.24
hydroxyacid-oxoacid transhydrogenase
|
–
|
|
|
BRENDA:
BS189012
|
|
|
|
beta-hydroxybutyrate + 2-oxoglutarate <=> succinate_semialdehyde + (R)-2-hydroxyglutarate
|
1.1.99.24
hydroxyacid-oxoacid transhydrogenase
|
–
|
|
|
BRENDA:
BS386124
|
|
|
|
4-hydroxybutyrate + 2-oxoglutarate <=> succinate_semialdehyde + 2-hydroxyglutarate
|
1.1.99.24
hydroxyacid-oxoacid transhydrogenase
|
–
|
|
|
BRENDA:
BS189009
|
|
|
|
4-aminobutanoate + 4,5-Dioxopentanoate <=> 5-aminolevulinate + succinate_semialdehyde
|
2.6.1.43
aminolevulinate transaminase
|
–
|
|
|
BRENDA:
BS356613
|
|
|
|
4-aminobutanoate + Vanillin <=> vanillylamine + succinate_semialdehyde
|
2.6.1.119
vanillin aminotransferase
|
–
|
|
|
BRENDA:
BS455030
|
|
|
|
succinate_semialdehyde + 3-acetylpyridine_adenine_dinucleotide + H2O <=> succinate + reduced_acetylpyridine_adenine_dinucleotide + H+
|
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
|
–
|
|
|
BRENDA:
BS451440
|
|
|
|
succinate_semialdehyde + H2O + Oxidized_benzyl_viologen <=> succinate + H+ + reduced_benzyl_viologen
|
1.2.7.5
aldehyde ferredoxin oxidoreductase
1.2.7.B2
|
–
–
|
|
|
BRENDA:
BS359406
|
|
|
|
3-hydroxypropionate + NADP+ <=> succinate_semialdehyde + NADPH
|
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
|
|
|
BRENDA:
BS257249
|
|
|
|
2-(Acetamidomethylene)succinate + 2 H2O <=> acetate + succinate_semialdehyde + NH3 + HCO3-
|
3.5.1.29
2-(acetamidomethylene)succinate hydrolase
|
–
|
|
|
BRENDA:
BS453340
|
|
|
|
D-glutamate + 2-oxoglutarate <=> CO2 + L-glutamate + succinate_semialdehyde
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
|
–
|
|
|
SABIO-RK:
7100
|
|
|
|
2-aminobutanoate + glyoxylate <=> succinate_semialdehyde + glycine
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
SABIO-RK:
13952
|
|
|
|
2,6-dichlorophenolindophenol + 2-oxoglutarate <=> CO2 + reduced_2,6-dichlorophenolindophenol + succinate_semialdehyde
|
1.2.4.2
oxoglutarate dehydrogenase (succinyl-transferring)
|
–
|
|
|
SABIO-RK:
15290
|
|